ABSTRACT
Doxazosin is an adrenergic alpha-1 receptor antagonist used to treat lower urinary tract symptoms that are common in prostatic hyperplasia. To our knowledge, few cases of gynecomastia and mastodynia, as a complication of adrenergic alpha-1 receptor antagonist, have been reported to date; no cases have been reported in Korea. We describe a case involving a 78-year-old man treated for prostatic hyperplasia with 13 months of doxazosin. He complained about unilateral gynecomstia and mastodynia. Five months after the discontinuation of doxazosin, the gynecomastia was significantly improved. This is the first reported case of gynecomastia and mastodynia associated with doxazosin use in Korea.
Subject(s)
Aged , Humans , Male , Doxazosin , Gynecomastia , Korea , Lower Urinary Tract Symptoms , Mastodynia , Prostatic HyperplasiaABSTRACT
Cardiovascular malformations, such as bicuspid aortic valve and coarctation of the aorta, are more prevalent in patients with Turner syndrome than in the general population. Here, we describe the case of a 35-year-old female with Turner syndrome who was admitted to our hospital with a fever caused by infective endocarditis. Aortic coarctation was diagnosed using computed tomography. The patient was treated with antibiotics and a stent was then implanted. Endovascular therapy using stents is a safe and effective treatment option for aortic coarctation in patients with Turner syndrome.
Subject(s)
Adult , Female , Humans , Anti-Bacterial Agents , Aortic Coarctation , Aortic Valve , Bicuspid , Endocarditis , Fever , Stents , Turner SyndromeABSTRACT
Relapsing polychondritis is an uncommon disease associated with inflammation in cartilaginous tissues throughout the body, particularly affecting the cartilaginous structures of ears, nose, joints, and respiratory tract. Several autoimmune diseases, including vasculitis, are associated with the concurrent relapsing polychondritis. However, ankylosing spondylitis primarily affecting the sacroiliac joints and spine is rare in patients with relapsing polychondritis. We report on a 54-year-old man with concurrently relapsing polychondritis and ankylosing spondylitis.
Subject(s)
Humans , Middle Aged , Autoimmune Diseases , Ear , Inflammation , Joints , Nose , Polychondritis, Relapsing , Respiratory System , Sacroiliac Joint , Spine , Spondylitis, Ankylosing , VasculitisABSTRACT
Our report focuses on the case of a pregnant woman with bipolar disorder, manic episode. The patient was treated with olanzapine from the 24th gestational week until delivery and during breast feeding. No adverse events occurred during pregnancy, and the outcome was healthy.
Subject(s)
Female , Humans , Pregnancy , Bipolar Disorder , Breast Feeding , Pregnant WomenABSTRACT
Our report focuses on the case of a pregnant woman with bipolar disorder, manic episode. The patient was treated with olanzapine from the 24th gestational week until delivery and during breast feeding. No adverse events occurred during pregnancy, and the outcome was healthy.